The Relations Between The United States And Cuba - 1487 Words

The turbulent relations between the United States and Cuba became more controversial since the Cold War. They reached their apex on 15th October 1962, when after realizing that the Soviet Union was developing missile bases in Cuba, President Kennedy started taking strong procedures against Cuba. Indeed in February 1962 he signed the Embargo, which has not yet been lifted but reached improvements after more than 50 years, in April 2015 during Barack Obama and Raul Castro presidency (Renwick and Lee, August 4, 2015). This report will look at the difficult relations between U.S and Cuba, giving an outline of the historical background, along with the explanation of the processes that guided the decision to normalise these relations. Moreover†¦show more content†¦Even though the United States had objections on Castro’s Communist philosophy, they accepted his regime (Suddath, April 15th, 2009). Nonetheless Castro’s government intensified commerce with the Soviet Union, nationalized U.S properties, and hiked up taxes on American importations; the United States answered by rising economic retaliation (Renwick and Lee, August 4, 2015). Another fundamental event on the relations between Cuba and The U.S was on January 3rd 1961 when The United States closed its embassy in Havana coming to an end with diplomatic ties with Cuba (Hudson, August 3rd, 2015). The worst period in their relations occurred when in October 1962, President Kennedy imposed the embargo on Cuba (Hudson, August 3rd, 2015). The slow process of normalising U.S and Cuban ties began secretly in 2013, but it became official only in December 2014, after 50 years of no diplomatic relations between the two countries. On December U.S President Barack Obama and Cuba’s President Raul Castro declared that they had exchanged prisoners to start the re-establishment of their diplomatic relations. This normalization of relations is a process that will continue for a long time, due to Cuba’s Human Rights matters and Havana’s request to maintain restraints on Cuba’s society and economy (Daily Mail, July 1st, 2015). On July 2015, President Obama released a statement on the

Product Team Cialis Getting Ready to Market - 780 Words

Differentiation Positioning Case: Product Team Cialis_Getting Ready to Market (HBS 9-505-038) The Actors: - Mark Babato, the executive director and global product team leader for Cialis - Rob Brown, the global marketing director from Lilly - Leonard Blum, vice president of sales and marketing from ICOS - Sidney Taurel, Chairman of the Board, President and CEO of Lilly Problem Analysis: | |VIAGRA |CIALIS | |The effect |approx. 4 hours after dosing |36 hours after taking the drugs | |The absorption |Diminished when†¦show more content†¦Global Marketing Research (GMR) 2. Global Marketing Planning (GMP) 3. Global Marketing Sales Training (GMST) In the initial stage of new product planning, GMSO had two roles: 1. For research projects based on the ongoing input from the sales-reps visiting physicians and market needs identified by GMR 2. For projects that seemed to have medical effectiveness in Phase I and II clinical trails, GMP would forecast market potential to see whether these products should be terminated or moved forward. Competitors: Pfizer: - Expanding more RD resources - Known as marketing prowess - DTC advertising was an important part of communication mix Bayer with Levitra: - Very effective at lower dosage than Viagra (as low 5 and 10mg) - Designed trials to focus on showing good results in diabetic men - The duration was roughly the same as Viagra - Bayer has conjunction with GlaxoSmithKline to expand its sales force in US market QUESTIONS: 1. Who should be the target market for Cialis? - Someone who has been used Viagra but discontinued the usage, or in other words can be called as a â€Å"dropouts†, for some reasons which probably dissatisfied with it. - Based on exhibit 6, the average of ED patient are men starting from 50 years old which employed full time and married or have sexual partner. - Based on exhibit 7a,Show MoreRelatedProduct Team Cialis: Getting Ready to Market832 Words   |  4 PagesLecture 10: Product Team Cialis: Getting Ready to Market (case 12) 1-) The most relevant dimensions along which to segment the patient market for the Erectile Dysfuction (ED) treatment are demographic, psychographic and behavioral dimensions. With demographic segmentation, we divide the market into groups on the basis of variables such as age, family size, family life cycle, gender, income, occupation, education, religion, race, generation, nationality and social class. The prevalence ofRead MoreEssay Product Team Cialis Getting Ready to Market1277 Words   |  6 PagesProduct Team Cialis: Getting Ready to Market MKT Q1. In 2002, Viagra was the only clinically proven, FDA approved medication for Erectile Dysfunction (ED) on the market (Cialis – Dec 2003, Levitra – Sept 2003). Viagra had the highest brand recognition of any pharmaceutical product on the market. It had generated over one billion dollars in annual sales for 3 consecutive years since its introduction in 1998. In 2002, Viagra accounted for 5.3% ($1.73 billion) in sales of Pfizer’s annualRead MoreProduct Team Cialis: Getting Ready to Market Essay3273 Words   |  14 Pages1. What are the most relevant dimensions to use to segment the patient market for ED treatment? Select only the most relevant! The most relevant dimensions to use in order to create useful segments for Cialis are: 1. Age 2. Demographic Demographic Marital Status 3. Income 4. Education 5. Psychographic Psychographic Life Stage/Occupation (Student, Employed or Retired) 6. Values 7. Usage Patterns Firstly, age is a valuable dimension due to the strong positive correlationRead MoreCialis - Harvard Business School Case: Product Team Cialis: Getting Ready to Market1439 Words   |  6 Pages1.Problem StatementLilly- ICOS LLC is about to launch a new and innovative product intended to help men suffering from Erectile Dysfunction (ED). Because of the unique product features, Cialis - the product - has good chances of becoming successful even though it is entering a segment, where Pfizers Viagra is the undisputed market leader. In this context, Lilly- ICOS LLC must decide on a marketing strategy, in particular which groups to target and which positioning thus which communication strategyRead MoreCialis Case Essay9153 Words   |  37 PagesHARVARD BUSINESS SCHOOL 9-505-038 REV: JUl Y 2 8. 201 0 ElIE OFEK Product Team Cialis: Getting Ready to Market It was early 2002, and Mark Barbato, the executive director and global product team leader for Cialis, knew he faced a daunting task: launching a medicine for the treatment of male impotence in a market with an established leader-Viagra. 1 Not only had Viagra been generating over $1 billion in sales annually for its parent company Pfizer for three consecutive years, butRead MoreCialis Hbs Case986 Words   |  4 PagesProduct Team Cialis Getting Ready to Market 1.- What trends you think could influence positively and negatively the ED market? The usual market for medication has only main target audience: doctors. They are the ones that will need to be ‘sold’ on the product while patients will mostly take whatever they are prescribed. This case is slightly different due to the fact that 1) the brand Viagra has an unusual high awareness among patients, and 2) the influencing factor of partners is high. ThisRead MoreCase Analysis Cialis Essay1608 Words   |  7 PagesTracy Rucker Marketing Mid-Term 2012 March 1, 2012 Product Team Cialis: Getting Ready to Market Brief Background Erectile dysfunction’ is the failure to achieve and maintain an erection sufficient for satisfactory sexual experience. It affects 150 million men globally. In March1998, Viagra (Sildenafil) was the first oral medication approved for use in ‘erectile dysfunction. Viagra had a very successful launch with a total of 600,000 prescriptions filled in the first month (April 1998), andRead MoreCase Study - Cialis - Ready to Market6941 Words   |  28 PagesTable of Contents: Team Cialis A) Introduction†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦3 B) Situation Statement†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.3 C) SWOT analysis†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦5 1. Environment†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦5 a. Opportunities b. Treats 2. The Firm†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦8 a. Strengths b. Weaknesses D) Options Generated†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.10 E) Recommendations†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦13 F) Suggested Plan of Implementation†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦16 Read MoreStrategic Marketing Management337596 Words   |  1351 Pages215 221 223 223 230 236 241 246 248 250 251 255 261 4 Market and environmental analysis 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 4.10 Learning objectives Introduction: the changing business environment (or the new marketing reality) Analysing the environment The nature of the marketing environment The evolution of environmental analysis The political, economic, social and technological environments Coming to terms with the industry and market breakpoints Coming to terms with the very different future:

Movie Analysis Mrs. Doubtfire - 1629 Words

Introduction Health practitioners must understand that family systems play a role in the health of the individual family members. For example, in a household with increases tension children might present with physical manifestations of anxiety. Further, the belief system of the family can have an impact on the healthcare decision making. To better understand family systems and roles the film Mrs. Doubtfire will be utilized as a case study for family assessments. Movie Setting and Story The film Mrs. Doubtfire is about a family who is in some turmoil. The mother (Miranda) of the family has requested a divorce from the husband (Daniel) and has denied him custody of their three children (Lydia, Chris, and Natalie). In response, the husband chooses to dress up as an elderly woman and is hired as the housekeeper and children’s nanny (Mrs. Doubtfire). The film portrays divorce using a comedic element. After the Mrs. Doubtfire is revealed to be the husband in disguise the mother petitions the court and is granted full custody. However, the children do not adjust to this change well. The children’s difficulty adjusting to the change prompts Miranda to seek out Daniel to change the custody arrangement. At the end of the movie, it is revealed to the children that the father will continue in his caregiving role without a disguise. Assessment of Movie Family This family is an upper-middle class Caucasian family living in an urban environment. The parent’s divorce has impacts on theShow MoreRelatedTelemetry 1011124 Words   |  5 Pages[pic] Movie Family Analysis Submit by 2359 Sunday of Week 1. |Name: | |Date: | | Overview Choose a movie from the provided list. Watch the movie, focusing specifically on the family unit featured in the film. Compare and contrast the movie family’s characteristics and behaviors to the assessment criteria introduced in the class notes and readings from the

Designing and Implementing Paperless †Free Samples to Students

Question: Discuss about the Designing and Implementing Paperless. Answer: Introduction: The process of learning has become one of the most joyful and worthwhile experience. The learning programs and the information mastery has been useful in my learning life and will be of great help in my career life and my life generally. This reflective journal focuses on the learning experience to assess what we have learned from the challenges faced in efforts to overcome business challenges. The learning process is featured concerning what worked well or what did not work well as a learner. Some of the learning aspects were so welcomed in my learning experience while others still need to be rectified for better achievement of results. In the field of commerce that is closely related to the business world, I have been able to interact, learn, and gain new experiences on how to handle business challenges. My desire to become a successful business person, driven by the virtue of entrepreneurship has kept me moving and always focussed to learning new experiences on how to venture in n ew innovative businesses. This article explains the importance of the learning experiences I have gained while in the coursework and interactions from the successful business people in the business world. The current advancement in technology has necessitated numerous alterations in the learning process which requires one to be on the know-how of the computer so as to develop the necessary learning skills. This is made possible by having the required tools such as the tablets and the laptops which help in keeping one updated and enhances the learning process (Hesser Schwartz, 2013). By the end of the learning process, I was able to concentrate on a certain subject for quite long hours than before with a focused mind to understand the content unlike before whereby I could not withstand staring at a book or reading material for more than an hour. I realized the importance of the learning gadgets which include the laptops and that they are not only meant for entertainment but for enhancing the learning process. A good learning experience, especially in this dynamic world of technology, can be a great and wonderful experience since it can create engaging, relevant, and notable educational experiences which address certain challenges faced by the learners. The learning experience is beneficial especially to people who would want to get involved in business transactions since the trend is ever-changing and this helps one to become accustomed to the business world dynamics without a struggle (Kao et al, 2014). The learning experience also helps one to widen their minds in terms of business dealings hence able to identify the emerging opportunities to venture into. Thus, the learning experience should be improved and make it more effective. The learning experience has great value in a persons life generally. Firstly, it ensures that one is fully-equipped with the current trends in the world. One cannot engage in a business that they are not aware of the dynamics involved in the kind of business they would want to venture into (Johnson et al, 2012). Again, the learning experience enables one to evaluate the kinds of businesses that are easy to carry out and the requirements needed thereof. One is able to assess the type of risks each business is prone to and the amount of capital required to start a certain business. The learning experience exposes one to many kinds of people such that it becomes easy to transact a business with all types of people with different backgrounds. The learning experience enables one to choose a course wisely based on their talents and areas of interest. As one develops a learning experience, he or she is able to identify the kind of course which they can fit better and put their whole efforts towards improving on those areas and leave alone those that they are not talented in (Ellaway et al, 2014). The relevance of the course is determined by the learning experience in such a course. This will help one to choose a course which they feel will benefit them the most and which their passion is directed to and this guarantees good performance in such a course. It helps one to prioritize their time and activities wisely. The setting of priorities are important aspects of learning which enables one to attend first to the important things and give significant attention to them to avoid unnecessary mistakes. The proper scheduling of events with their appropriate time is significant towards the success of all my ambitions to become a successful business person and a decision maker in matters that require prompt action. Working without any set or established priorities leads to the creation of conflicts and the establishment of petty mistakes that leads to business failure. My ability to make the right priorities and assign the correct time would help me become the best decision maker in my commerce profession. The learning experience is a good determinant of the kind of career one is likely to engage in future. Through learning, one is able to discover their talents and abilities to perform in a certain area and this guides the type of career to choose. The areas of interests are vital since one realizes that there are some areas which they can perform better than others (Shek et al, 2015). This helps to eliminate those that are difficult to understand or are of less interest. It also helps to identify the areas which may need to be improved in future. During the learning process, I was exposed to various lifestyles, languages, and cultures which played as an adventure kind of life. Thus, transacting business with various people and business environment was somehow enhanced. Having a wide range of knowledge and information is useful in the organization as the ability to solve critical issues is advanced. During the learning process, I interacted with many people from different backgrounds and this will help me to adapt to new challenges and environments. I read about how to set both short and long-term goals and the merits of each. I heard of the various business expositions and seminars and the advantages of attending them. My objective of learning commerce principles is assisting me realise and exploit my full potential of the dream to become a successful business manager. Evaluate what you learn Venturing into a business is a wise idea and a good way to build ones career. However, it requires one to first have the idea and be focused on evaluating the potential risks and benefits of running a certain business. It is also important to scrutinize the market structure and understand the potential competitors. My learning experiences can be viewed as a success, and not a failure. This is because I have been properly equipped with the right skills to scrutinize the underlying challenges that face a company and come up with amicable solutions regarding the problems. Doing a research on the market structure was a critical assignment since it is the determinant of any business success. Identifying the best business types and how they are run and the possible outcomes of the business was an important activity so as to assess whether to venture into such a business or not. Therefore, doing the activities in task one and two was designed to equip me with the right skills to solve business challenges, understand business trends and needs, and understand which business venture is right to invest by a business person. Explain Plan how this learning you will apply The learning will be useful in my career life. Having interacted with various people and cultures, I will be able to transact business without fear as it will be easy to analyse the business situations. I will also be able to consult business experts in any particular area of interest to expand my business ideas. Generally, the learning experience has enlarged my mind hence built both my personal and career life. Learning helps people both professionally in in their personal lives. I would apply my learning experiences in the creation and innovation of new business ideas that would thrive in the economy. Further, I would apply my learning experiences of conflict resolution approaches in the resolving of wrangles among any conflicting parties in the work place. Looking forward to become a family person, understanding the importance of tolerance and the facts that people show differences in their approaches to different matters, I would be tolerant and always understanding so as to bri ng peace in the family. Furthermore, learning the principles of conducting business and ensuring that it thrives would be helpful to me when applying such principles into practice. This practice would involve the laying down policies that protect the rights of everyone in the industry as well as ensuring that all the identified opportunities in the minimum risks and costs as possible. References Ellaway, R. H., Fink, P., Graves, L., Campbell, A. (2014). Left to their own devices: medical learners use of mobile technologies.Medical teacher,36(2), 130-138. Press. Hesser, T. L., Schwartz, P. M. (2013). iPads in the science laboratory: Experience in designing and implementing a paperless chemistry laboratory course.Journal of STEM Education: Innovations and Research,14(2), 5. Press. Johnson, L., Adams, S., Cummins, M. (2012).Technology Outlook for Australian Tertiary Education 2012-2017: An NMC Horizon Report Regional Analysis. New Media Consortium. 6101 West Courtyard Drive Building One Suite 100, Austin, TX 78730. journal of nursing education scholarship,11(1), 75-82. Press. Kao, A. B., Miller, N., Torney, C., Hartnett, A., Couzin, I. D. (2014). Collective learning learning arena for developing shared work practices. InAgency at Work(pp. 351-371). Press. Khan, A. I., Al-Shihi, H., Al-Khanjari, Z. A., Sarrab, M. (2015). Mobile Learning (M- Learning) adoption in the Middle East: Lessons learned from the educationally advanced countries.Telematics and Informatics,32(4), 909-920. Lamont, A. (2012). Emotion, engagement and meaning in strong experiences of music performance.Psychology of Music,40(5), 574-594. Najjar, R. H., Lyman, B., Miehl, N. (2015). Nursing students experiences with high-fidelity nursing students.International Journal of Nursing Education Scholarship,10(1), 255- Page, T. (2014). Application-based mobile devices in design education.International Journal of Mobile Learning and Organisation,8(2), 96-111. Press. Sharma, V., van de Graaff, S., Loechel, B., Franks, D. (2012). Extractive resource development in a changing climate: Learning the lessons from extreme weather events in Queensland, Australia. Press. Shek, D. T., Yu, L., Wu, F. K., Ng, C. S. (2015). General education program in a new 4- simulation.International Journal of Nursing Education Scholarship,12(1), 27-35. Press. Wanner, T., Palmer, E. (2015). Personalising learning: Exploring student and teacher perceptions about flexible learning and assessment in a flipped university course.Computers Education,88, 354-369. Press.

The transformation in the fortunes of the Nazi part in the years 1930-1933 was largely because of Hitlers talents as a politician how far do you agree with this opinion free essay sample

In the early twentieth century the Nazi party (NSDAP) was a small extremist party renowned for its use of violence and its beliefs such as anti-Semitism and anti-marxism. The party believed that the treaty of Versailles was wrong and unfair thus needed opposing; this was done through a military coup that ultimately failed due to a lack of support. However between 1930 and 1933 the fortunes of the Nazi party completely changed, this transformation was not only due to Hitler’s talents as a politician but also his personality, the use of propaganda, political manoeuvring, the change in support and the use of the SA and violence. Prior to 1930 Hitler allied himself to Alfred Hugenberg in opposing the young plan, this aided the parties future growth and political prestige as it provided them with both financial and political support. This allegiance made the party seem less radical and less suspicious, Hitler could use this to his advantage as it supplied them with new respectability and national stature. We will write a custom essay sample on The transformation in the fortunes of the Nazi part in the years 1930-1933 was largely because of Hitlers talents as a politician how far do you agree with this opinion? or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page This change in public views can be seen in election results from the late 1920s and the early 1930s; in 1928 the party had 0. 8 million voters, where as in 1932 there was a significant increase as the July elections showed the Nazi party had 13.7 million voters. This change in support was largely due to Hitler’s skills as a politician and the manipulation propaganda provided in aiding him. The organisation of the party allowed Hitler to organise areas into a specific group (Gaul) that was directly answerable to him; this allowed him to target the needs of each individual area and in doing so focus on solving their problems. This use of organisation and political manoeuvring highlighted Hitlers strength as a politician through his ability to focus on problems that affected the welfare of German society such as unemployment. Hitler’s personality also aided his ability to be such a skilled politician; his ability to empathise and identify peoples emotions and expectations made Hitler attractive to the German people amid the despair of economic crisis when other parties seemed to lack a sense of direction. Another use of political manoeuvring and propaganda Hitler implicated was the use of targeting rural areas of Germany; this showed Hitler talents as a politician as targeting the less urbanised or industrial areas meant there was less competition from rivalling parties who were targeting densely populated areas. On the other hand it was not only Hitlers talents as a politician that allowed the Nazi prestige to grow but rather the abilities of Goebbels who was Hitler’s propaganda advisor throughout his campaign. Goebbels abilities as propaganda advisor was vital to Hitler becoming chancellor in 1933 and the furthering of Hitler’s political career. The propaganda Goebbels provided emphasised family values and German traditions which proved popular with women and succeeded ion procuring their votes and support. It was not only these themes that influenced German support but also the many militaristic processions that took place and their (the Nazi’s) general decisive power; typical of the old government. The processions in addition to their emphasis of other themes increased the support for the Nazi party and pulled voters away from the weakening Weimar republic. However Hitlers personality combined with Goebbels propaganda also proved popular and gained many votes as Hitler was a very charismatic public speaker. Goebbels also highlighted Hitlers anti-Semitic policy which proved to be successful, as did his policies on communists/foreigners and the November criminals. Hitler and Goebbels provided the public with someone to blame and made the Nazi party more attractive. The use of the SA or storm detachment also aided in changing the fortunes of the Nazi party in the early 1930s. The SA was formed in 1920 and was made up of ex-soldiers who were to provide protection to Nazi speakers. This protection alone would have had little impact on public views except their propaganda by deed approach drew attention to the communist threat and the Nazi determination to destroy it; which proved successful in gaining support from the German people. By 1932 the Nazi party was the biggest in the Reichstag with 37% of the votes and 230 seats, the changes in the Nazi parties fortunes would continue to change over the next two years due to political manoeuvring and Hitler’s abilities as a politician. Following the July election Hitler requested to become chancellor; however Hindenburg refused and appointed Von Papen instead, subsequently his appointment-ship was based on a coalition with the Nazi party because of their voting power. Hitler would again request to become chancellor after the November elections of 1932, again Hindenburg rejected his proposal and again appointed Von Papen. However Papens reappointment as chancellor angered Von Schliecher who had previously been allied with Papen against Hitler;because he himself wanted the chancellorship. By the latter end of 1932 Papen had lost most of his support and Hindenburg was forced to appoint Von Schliecher in Papens stead. In 1933 The changing fortunes of the Nazi party became obvious as Hitler Was made chancellor of Germany. This transformation highlighted Hitler’s talents as a keen politician and the support he had gathered from the German people; his chancellorship came into being not only because of the support or abilities he possessed but also because of Goebbels skills and his allegiance with Von Papen who had sort to aid Hitler’s so he could become vice chancellor. Throughout the years 1930 and 1933 the transformation of the Nazi parties fortunes was fundamentally due to Hitler’s personality and his talents as a politician; these talents were significantly aided by Goebbels propaganda and the support he was provided with by the disgruntled German people. Towards the latter end of 1932 and the beginning of 1933 saw the birth of Hitler’s chancellorship and emphasised the change in fortunes the Nazi party had been privy too.

Hepatitis-B vaccine Essays

Hepatitis-B vaccine Essays Hepatitis-B vaccine Essay Hepatitis-B vaccine Essay ESCALETED DOSE OF HEPATITIS-B VACCINE IN CHILDHOOD HAEMATOLOGICAL MALIGNANCIES WHILE ON CHEMOTHERAPY. Abstract. This prospective survey was conducted to happen out an effectual inoculation agenda against hepatitis B infection for the kids with haematological malignances. 60 patients between 2-15 old ages with haematological malignances on chemotherapy, negative for HBsAg and neer vaccinated for HBV before, were vaccinated with 40 mgm of vaccinum at 0, 1 and 2 months. The antibody titre was measured 6 hebdomads after disposal of last dosage and analyzed. Out of 60 enrolled, 5 died during the class of intervention and 4 dropped out before completion, go forthing 51 for concluding analysis. More than 70 % exhibited protective degree of antibody ( A ; gt ; 10 mIU/ml ) against hepatitis B virus. There was no important consequence of age or sex on the antibody response, although it was higher among misss ( 90.9 % ) than male childs ( 65 % ) . Patients of non-Hodgkin s lymphoma were found to be in a better position to exhibit antibody response, compared to the leukemic kids ( P = 0.024 ) .This surve y concluded that haematological malignant neoplastic disease patients should be vaccinated with escalated doses of the vaccinum alternatively of the conventional doses. Introduction In childhood malignances, hepatitis B infection remains a major co-morbid status, which may impact the result of intervention ( Indolfi P et Al, 1992 ) . The high hazard for developing hepatitis B infection is due to immunosuppression secondary to chemotherapy, radiation therapy, multiple blood transfusions, endovenous medicines, every bit good as repeated invasive probes ( Meral A et Al, 2000 ) . Treatment with immunosuppressive drugs enhances the possibility farther of developing chronic bearer province or reactivation of HBV infection in symptomless bearers ( Ramesh M et Al, 2000 ) . This plays an inauspicious predictive function in their disease-free endurance because of holds in chemotherapy ( Meral A et Al, 2000 ) . Sing this high hazard of infection, kids with malignant neoplastic disease should be routinely vaccinated against hepatitis B. However, several surveies have shown that if vaccinated with conventional doses and agenda, the antibody titre against hepatitis B did non make the protective degree due to impaired immune response ( Indolefi P et Al, 1992 ; Mannan MA and Ghosh NK, 2003 ; Somjee S et Al, 1999 ) . We antecedently vaccinated 131 kids with malignant neoplastic diseases aged 2-15 old ages and 100 otherwise healthy kids of same age as control. All these kids were negative for hepatitis B markers. The dose and inoculation agenda used was 10 A ; micro ; gram for age A ; lt ; 10 old ages and 20 A ; micro ; gram for age A ; gt ; 10 old ages vaccinated at 0, 1 and 6 moths. The protective antibody degree ( A ; gt ; 10 IU/L ) measured 6 hebdomads after the last dosage was 10 % in the studied group compared to 98 % in the controls ( Mannan MA and Ghosh NK, 2003 ) . Several surveies have shown that utilizing the conventional dose of 10 and 20 A ; micro ; gram, a farther 4th, 5th or even 6th dose agenda as 0,1,2 and 6 ; 0,1,2,6 and 12 and 0,1,2,3,4 and 12 did non assist significantly to increase the antibody titre ( Mannan MA and Ghosh NK,2003 ; Drachman R et al,1989 ; Yetgin S et Al, 2001 ) . We, hence, decided to transport out the present survey with an escalated dose of 40 A ; micro ; gram of hepatitis B vaccinum ( Engerix B ) , irrespective of age, in childhood malignant neoplastic disease patients utilizing a agenda of 0, 1 and 2. Antibody titre was measured 6 hebdomads after disposal of the last dosage and if found amp ; gt ; 10 IU/L, was considered as protective. MATERIALS AND METHODS The survey was conducted at Bangabondhu Sheikh Mujib Medical University ( BSMMU ) , Dhaka from January to September 2006. Children go toing the Out-Patient and In-Patient Clinics of Pediatric Hematology and Oncology Department at BSMMU and a Private Clinic of a Pediatric Haemato-Oncology Specialist in Dhaka were recruited for the survey. The age bound was between 2 to 15 old ages with a diagnosing of either Leukemia or Lymphoma. All the kids recruited were in the care stage of chemotherapy and antecedently non vaccinated for hepatitis-B. Those with HBsAg positive every bit good as anti HBsAg positive were excluded. A entire figure of 60 kids were enrolled for the survey. An informed written consent was obtained from the parents. The households were besides informed that they would be able to retreat their kids from the survey at any clip they wanted ( Helsinki Declaration for Medical Research Involving Human Subjects 1964 ) . Inoculation plan: Recombinant hepatitis-B vaccinum was given intramuscularly at 40 mgm per dosage at 0, 1 and 2 months, irrespective of age. The generic merchandise of Glaxo-Smithkline Pharmacuticals Ltd. ( Engerix-B ) was used for the survey. Blood trial was performed utilizing Kit- ELISA method to mensurate antibody for HBsAg 6 hebdomads after disposal of the 3rd dosage. Antibody titre A ; gt ; 10 mIU/ml was considered as protective. Detail information about the kid, haematological malignance including type, phase, age at diagnosing, specific intervention for malignance and present wellness position were collected from the medical and research lab records. Inoculation day of the month and blood trial studies were recorded meticulously. All informations were plotted and analyzed utilizing the SPSS for Windows ( Version 10.2 ) . Descriptive analysis was performed that included chi-square trial, mean, average and SD. Cut off p-value or degree of significance was A ; lt ; 0.05. Consequence A sum of 60 patients of were enrolled into the survey. Five of them died of the disease before mensurating antibody degrees and 4 dropped out during follow up. Therefore, entire 51 patients remained for concluding analysis. The age bound was between 2 to 15 old ages ; 17 ( 33.3 % ) were below 5 old ages of age, 28 ( 54.9 % ) were between 5 to 10 old ages and the remainder 6 ( 11.8 % ) were above 10 old ages ( Table I ) . On the other manus, a sum of 40 ( 78 % ) patients were male, and merely 11 ( 22 % ) were female ( Fig 1 ) . Table I. No of per centum of patients by age ( n = 51 ) : Age ( yrs ) # % A ; lt ; 5 17 33.3 5 10 28 54.9 A ; gt ; 10 06 11.8 Average = ( 6.16 A ; plusmn ; 3.14 ) old ages ; scope = ( 2 15 ) old ages. Out of 51 patients, 29 ( 56.9 % ) were diagnosed as holding leukaemia and the remainder 22 ( 43.1 % ) had lymphoma. Out of those 29 with leukaemia, 26 ( 51 % of entire 51 ) had ALL and 3 ( 5.9 % of 51 ) had AML. On the other manus, out of 22 with lymphoma, 20 ( 39.2 % of 51 ) had non-Hodgkin s Lymphoma, and the remainder 2 ( 3.9 % of 51 ) had Hodgkin s lymphoma ( Table II ) . Table II. No of per centum of patients by diagnosing ( n = 51 ) : Diagnosis No % ALL 26 51.0 AML 03 5.9 Hodgkin s disease 02 3.9 Non-Hodgkin s lymphoma 20 39.2 Table III shows the per centum of patients by antibody response in the blood measured 6 hebdomads after disposal of 3rd dosage of hepatitis B vaccinum. Over 70 % of the patients demonstrated protective degree of antibody. The average antibody degree was 125.0 A ; plusmn ; 17.09 mIU/ml. Table III. No of per centum of patients by antibody response ( n = 51 ) : Antibody titre ( mIU/ml ) No % A ; lt ; 10 15 29.4 A ; sup3 ; 10 36 70.6 # Median = ( 125.0 A ; plusmn ; 17.09 ) mIU/ml. Table IV. Association between age and antibody response ( n = 51 ) : Age ( year ) Antibody titre ( mIU/ml ) p-value # A ; lt ; 10 ( n = 15 ) A ; sup3 ; 10 ( n = 36 ) A ; lt ; 5 5 ( 33.3 ) * 12 ( 33.3 ) 0.752 5 10 1 ( 6.7 ) 5 ( 13.9 ) A ; lt ; 10 9 ( 60.0 ) 19 ( 52.8 ) * s in the parentheses denote matching % . # Chi-square ( c2 ) Trial was done to analyse the information ; degree of significance was 0.05. Table IV shows the association of age with antibody response. No peculiar age group was found to be more immunogenic than the others to show antibody response following hepatitis B inoculation ( p A ; gt ; 0.05 ) . Table V. Association between sex and antibody response ( n = 51 ) : Sexual activity Antibody titre ( mIU/ml ) p-value # A ; lt ; 10 ( n = 15 ) A ; sup3 ; 10 ( n = 36 ) Male 14 ( 35.0 ) 26 ( 65.0 ) 0.093 Female 1 ( 9.1 ) 10 ( 90.9 ) * s in the parentheses denote matching % . # Fisher s Exact Test was done analyze the information ; degree of significance was 0.05. Table V demonstrates the association between sex and antibody response. The proportion of misss developing protective antibody was observed to be higher ( 90.9 % ) than that of male childs ( 65.0 % ) . However, the difference did non make the degree of significance ( p A ; gt ; 0.05 ) . Table VI. Association between diagnosing and antibody response ( n = 51 ) : Diagnosis Antibody titre ( mIU/ml ) p-value # A ; lt ; 10 ( n = 15 ) A ; sup3 ; 10 ( n = 36 ) Leukemia 11 ( 37.9 ) * 18 ( 62.1 ) 0.125 Lymphoma 4 ( 18.2 ) 18 ( 81.8 ) * s in the parentheses denote matching % . # Fisher s Exact Test was done analyze the information ; degree of significance was 0.05. Table VI demonstrates the antibody response of patients based on diagnosing. The patients with lymphoma exhibited a higher rate of protective antibody degree ( 81.8 % ) than the patients with leukaemia ( 62.1 % ) , although the difference did non turn to be important ( P A ; gt ; 0.05 ) . Table VII. Association between type of malignance and antibody titre ( n = 51 ) : Type of malignance Antibody titre ( mIU/ml ) p-value # A ; lt ; 10 ( n = 15 ) A ; sup3 ; 10 ( n = 36 ) ALL 10 ( 38.5 ) * 16 ( 61.5 ) 0.024 AML 1 ( 33.3 ) 2 ( 66.7 ) Hodgkin 2 ( 100.0 ) 00 Non-Hodgkin 2 ( 10.0 ) 18 ( 90.0 ) * s in the parentheses denote matching % . # Chi-square ( c2 ) Trial was done to analyse the information ; degree of significance was 0.05. Table VII demonstrates that 90 % of the non-Hodgkin s lymphoma had protective degree of antibody, while 61.5 % of ALL and 65.7 % of AML had protective degree of antibody. The association between non-Hodgkin s disease and antibody response against hepatitis B inoculation was found to be important ( p = 0.024 ) . Discussion Hepatitis B inoculation can bring on seroconversion in 65-95 % of healthy kids ( Jilg W et Al, 1989 ) . The present survey demonstrated that more than 70 % of the topics developed protective degree of antibody titre ( A ; gt ; 10 mIU/ml ) 6 hebdomads after disposal of 3rd dosage of 40 mgm of recombinant HBV vaccinum. No unwanted side-effects, except hurting and inflammation at the site of injection, were encountered by the topics. In our old survey where 10 mgm of vaccinum was used in kids A ; lt ; 10 old ages of age and 20 mgm in older kids at 0, 1 and 6 months, the protective degree of antibody in the malignant neoplastic disease group measured 6 hebdomads after the last dosage was merely 10 % compared to 98 % in the control opposite number ( p A ; lt ; 0.01 ) ( Mannan MA and Ghosh NK, 2003 ) . In the 2nd stage of the same survey, inoculation plan was rescheduled with figure of doses increased from 3 to 4 and were given at close intervals ( 0, 1, 2 and 6 months ) . The consequen ces obtained showed that protective antibody degree in malignant neoplastic disease group reached from enormously low 10 % to 57 % ( unpublished information ) . Three series of surveies therefore conducted show that escalated dose aid a considerable figure of immune-compromised kids grow protective degree of antibody against hepatitis B. Meral et Al utilizing an escalated dosage at 0, 1, 2 and 12 months achieved a serconversion rate of 75 % in patients with haematological malignances following first three doses and 86 % after completion of 4 doses bearing consistence with findings of the present survey. In the present survey a significantly higher proportion of lymphoma patients demonstrated higher degrees of protective antibody ( 90 % ) than that in leukaemia ( 61.5 % ) . Meral s survey, on the other manus, showed that patients with lymphoma had the least response compared to patients with leukaemia and solid tumours ( p = 0.0003, P = 0.0161 ) . The ground of this disagreement might be that in our survey bulk of the lymphoma patients had non-Hodgkin s disease, whereas in their survey most of the kids with lymphoma had Hodgkin s disease, which might play a function in the lessened response to inoculation owing to basic cellular immune upsets associated with the disease ( Goyal S et Al, 1998 ) . Furthermore, in their survey, the kids with lymphoma and solid tumours were vaccinated at diagnosing when they had the most intensive chemotherapy. This might do more immunosuppression in them. Pervious similar surveies besides demonstrated impaired immune response to active inoculation in ki ds with leukaemia during intensive chemotherapy ( Hudson MM and Donaldson SS, 1997 ; Berberoglu S et Al, 1995 ) . In the Meral s survey, 86 % of the to the full immunized kids ( 4 doses completed ) developed lasting anti-HBs positiveness. Serconversion rates with regard to diagnosis were 90.3 % in leukaemia, 74 % in lymphoma and 94.4 % in solid tumours. Serpositivity increased from 48 % to 74 % in lymphoma and from 77 % to 94 % in solid tumours after 4th dosage. Berberoglu et Al, besides demonstrated that seropositivity increased from 56 % at 6 months to 70.5 % at 12 months after the 4th dosage. A inoculation plan was conducted by Indolfi et Al, on 80 patients aged between 1-15 old ages, holding negative serology for hepatitis-B and with normal liver map utilizing a recombinant DNA hepatitis-B vaccinum at doses of 40 mgm at close intervals ( 0, 1, 2 months ) with a supporter dosage at one twelvemonth. A 4th dosage ( 40 mgm ) was given at the 4th month to patients who did non react to three doses. Sixty-one kids, 38 with diagnosing of leukemia/lymphoma and 23 with solid tumours, completed the scheduled class. Over half ( 52.45 % ) of the topics responded with anti-HBs titre of A ; gt ; 10 mIU/ml further stressing the significance of escalated dosage of HBV inoculation in immune-compromised kids. However, studies of low antibody response even after utilizing escalated dose and figure of inoculation is no less. Ramesh et Al, showed that merely 28.6 % of the topics mounted an antibody response making protective value of A ; gt ; 10 mIU/ml after four dual doses of recombinant hepatitis B vaccinum. Similar observations were in an earlier survey ( Hudson MM and Donaldson SS, 1997 ) where merely a 3rd ( 32 % ) of the paediatric malignant neoplastic disease patients on chemotherapy mounted a protective response with figure of respondents being similar in haematological and solid malignances. Rokicka-Milewska et Al, administered active immunisation in kids with leukaemia and lymphoma. They showed that antibody titres were much higher in patients vaccinated after surcease of chemotherapy than those vaccinated in the class of care intervention. Goyal et Al, vaccinated leukemic kids at diagnosing, and merely 10.5 % of them had protective antibody titres. In their survey, 48.8 % of kids were infected with HBV. Their informations demonstrated that inoculation during the intensive chemotherapy period was non effectual. This might be a consequence of immunosuppression induced by both the disease and the intervention with cytotoxic drugs that diminished the response to inoculation. Therefore inactive immunisation with hyper Ig followed by active immunisation after the surcease of intensive chemotherapy could be a better option in these kids. Pilecki O et Al, used both inactive and active immunisation in kids with haematological proliferative diseases. They besides reported that usage of both active and inactive immunisation helped cut downing the rate of HBV infection aggressively from 43.3 % to 2.56 % . Surveies sing hepatitis B inoculation in kids with malignant neoplastic disease have observed the effects of age, sex and tumour and vaccinum type on antibody response. This response has been reported to be better in kids younger than 10 old ages and in misss ( Berberoglu S et Al, 1995 and Hollinger BF, 1989 ) . Different surveies stated that highest antibody responses were obtained in solid tumour groups since impaired figure of maps of lymph cells cause hapless vaccinum response in lymphoreticular malignances ( Meral A et Al, 2000 ; Hudson MM and Donaldson SS, 1997 ; Lehmbecher T et Al, 1997 ) .Corapcioglu et Al, nevertheless, did non happen any consequence of age and sex vaccinum and tumour type on antibody response. In our survey, no important consequence of age on antibody response was revealed. However, protective degree of antibody was demonstrated to be higher among misss ( 90.9 % ) than that among male childs ( 65 % ) , although the difference did non make the degree of sign ificance ( p = 0.093 ) . As serconversion was compared in footings of tumour type, patients of non-Hodgkin s lymphoma were found to be in a better place to exhibit important degree of antibody, compared to the leukemic kids ( P = 0.024 ) . Decision This present survey concludes that haematological malignant neoplastic disease patients classified as A ; lsquo ; non-responders after being vaccinated with conventional doses are really non so. Rather, they need a higher dosage to excite their already compromised immune system, because most of these kids responded to the escalated dosage of the vaccinum. Mentions Berberoglu S, Buyukpamukco M, Sarialioglu F et Al. Hepatitis B inoculation in kids with malignant neoplastic disease. Pediatr Hematol Oncol 1995 ; 12: 171-78. Corapcioglu F, Sarialioglu F, Olgun Nuysal KM. A marking system for the effectivity of having intervention for malignant neoplastic disease. Turk J Cancer 2001 ; 31 ( 4 ) : 150-57. Drachman R, Isacsohn M, Rudensky B, Drukker A. inoculation against hepatitis B in kids and adolescent kids on dialysis. Nephrol Dial Transpl 1989 ; 4 ( 5 ) : 372-74. Goyal S, Pai S, Kelkar R, Advani SH. Hepatitis B inoculation in acute lymphoblastic leukaemia. Leukemia Research 1998 ; 22: 193-95. Hollinger BF. Factors act uponing the immune response to hepatitis-B vaccinum, Booster dose guidelines and vaccinum protocol recommendations. Am J Med 1989 ; 87: 36-40. Hudson MM, Donaldson SS. Hodgkin s disease. In: Pizzo PA, Poplack DG, editors Principles and pattern of paediatric oncology. Philadelphia: Lippincott-Raven Publishers ; 1997 ; 523-43. Indolfi P, Casale F, Mazzei A, La Manna A, Cutillo L, Calabria C et Al. Response to Hepatitis-B Vaccine in kids with malignant neoplastic disease. PROC twentieth INT CONGR PEDIATR RIO DE JANERIO. 1992 ; 111. Jilg W, Schimidt M, Dienhardt F. Vaccination against hepatitis B: comparing of three different inoculation agendas. J Infect Dis 1989 ; 160: 766-69. Lehmbecher T, Foster C, Vazquez N et Al. Therapy-induced changes in host defence in kids having for malignant neoplastic disease. J Pediatr Hematol-Oncol 1997 ; 19: 399-417. Mannan MA, Ghosh NK. Redeuced Immunocompetence in Children with Cancer Bangladesh Journal of Child Health 2003 ; 27 ( 2 ) : 25. Meral A, Sevinir B, Gunay U. Efficacy of Immunization against Hepatitis B Virus Infection in Children with Cancer. Medical and Pediatric Oncology 2000 ; 35: 47- 51. Pilecki O, Wysocki M, Styczynski J et Al. Efficacy of inactive and active Immunization against HBV infection in kids with neoplastic disease. Pediatr Pol 1995 ; 395-99. Ramesh M, Marwaha RK, Chawla YK, Trehan A. Serconversion after hepatitis B inoculation in kids having malignant neoplastic disease chemotherapy. Indian Pediatrics 2000 ; 37: 882-86. Rokicka-Milewska R, Jackoska T, Sopylo B et Al. Active immunisation of kids with leukaemia and lymphomas against infection by hepatitis B virus. Acta Pediatr Jpn 1993 ; 35: 400-3. Somjee S, Pai S, Kelkar R, Advani S. Hepatitis-B Vaccination in Children with Acute Lymphoblastic Leukemia: Consequences of an Intensified Immunization Schedule. Leuk Res 1999 ; 23 ( 4 ) : 365-67. Yetgin S, Tunc B, Koc A, Toksoy HB, Ceyham M, Kanra G. Two supporter dosage Hepatitis B virus inoculation in patients with leukaemia. Leukemia Research 2001 ; 25: 647-49.

Economic Tiger Essay Example | Topics and Well Written Essays - 500 words

Economic Tiger - Essay Example Singapore is one of the leading economies in the world and is one of the economic tigers experiencing rapid economic progress over the period of time. Though smaller in geographical size, Singapore is considered as one of the leading economic hubs in international economy. One of the essential characteristics of the growth rates achieved by Singapore was its highly skilled and educated labor force. (Tulshyan, 2010). It is also important to note that the Singapore, as against other countries in the block, developed itself also as a financial hub of the region rather than achieving the growth mainly through industrialization. The overall economic growth is attributed to the export led growth which is mostly controlled through the state owned institutions. (Medina, 1996). Export of chemicals, refined oil as well as electronics are the main source of revenue for the country. Though geographically Singapore may be at disadvantage owing to its overall size and proximity with other countrie s, however, Singapore has been able to achieve the economic growth through a mixture of economic liberalization and state controlled institutions which are supporting the economy and creating the required level of economic prosperity.